First Experiments on Radioimmunodetection with b-12-Monoclonal Antibody Fragments against Breast Cancer Antigen^[*]

In 14 patients with breast cancer the results of radioimmunoscintigraphy with ¹²³l-labeled b-12 monoclonal antibody fragments were correct in more than two thirds of the patients.

Zusammenfassung

Bei 14 Patienten mit Mammakarzinom zeigte die Radioimmunszintigraphie mit ¹²³J markierten b-12 monoklonalen Antikörperfragmenten bei über zwei Drittel aller Patienten ein richtiges Ergebnis.

^* Presented at the Symposion on “Monoclonal Antibodies in Nuclear Medicine” in Freiburg i.Br., May 1-3, 1986.

• REFERENCES

• 1 Bradwell A, Fairweather D, Dylles P, Keeling A. Limiting factors in the localization of tumours with radiolabeled antibodies. Immunology Today 1985; 06: 163-70.
• 2 Stähli C, Takacs B, Miggiano V, Staehelin T, Carmann H. Monoclonal antibodies against antigens on breast cancer cells. Experientia 1985; 41: 1377-81.